Tesis doctoral de Jerusa Alecrim Andrade

The aim of this thesis is to discuss the results reached through two trials (trial 1 and trial 2) developed to reach a best methodological design to evaluate the role of acupuncture to prevent migraine attacks. Phase iii trial was done using the knowledge background obtained after these referred trials. subjects with migraine were randomized to the real or sham acupuncture groups in two different trials. distinctive treatment approaches were tested as being real acupuncture. In the first one, the individualized treatment was applied. The semi-standardized acupuncture treatment was evaluated in the second trial. All patients were treated with 16 acupuncture sessions during twelve weeks. Post-treatment follow-ups were done during 6-months. The primary endpoints adopted were the percentage of patients with reduction ¿40% (trial 1) and ¿50% in migraine attacks frequency (trials 1 and 2) and the total of days with migraine (trial 2). Headache diaries were used to obtain data in the baseline period and the full time of the study. Data from all diaries were compared with the baseline period. improvements with statistical significant differences appeared only in trial 1. Real acupuncture group was superior to sham group in the second month of the treatment, when the percentage of patients with ¿50% reduction in migraine attack frequency was evaluated (p=0.021). The reported differences appeared also in two secondary endpoints: number of days with migraine per month (p=0.007) in the second month of the treatment and in the first (p=0.044) and second (p=0.004) months of the treatment when the percentage of patients with a ¿40% reduction in migraine attack frequency was measured. the individualized treatment adopted in trial 1 seemed to be the best approach to test the acupuncture effects in trials for migraine prophylaxis.




 

Datos académicos de la tesis doctoral «Evaluation of the efficacy of acupuncture in the prevention of migraine attacks«

  • Título de la tesis:  Evaluation of the efficacy of acupuncture in the prevention of migraine attacks
  • Autor:  Jerusa Alecrim Andrade
  • Universidad:  Autónoma de barcelona
  • Fecha de lectura de la tesis:  18/07/2011

 

Dirección y tribunal

  • Director de la tesis
    • Francesc Xavier Carne Cladellas
  • Tribunal
    • Presidente del tribunal: miquel Vilardell tarres
    • José Miguel Lainez andres (vocal)
    • (vocal)
    • (vocal)

 





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